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The Abscopal Effect: A Game-Changer in Cancer Immunotherapy

09 Sep 2024

Article

Response Criteria in Pharmaceutical Clinical Trials: A Comparison of Structural and Functional Imaging

05 Aug 2024

Publications

In-depth cross-validation of human and mouse CD4-specific minibodies for noninvasive PET imaging of CD4+ cells and response prediction to cancer immunotherapy

02 Aug 2024

Article

Evaluating the immunologically “cold” tumor microenvironment after treatment with immune checkpoint inhibitors utilizing PET imaging of CD4+ and CD8+ T cells

25 Jun 2024

Abstract Presentations

2024 SNMMI Annual Meeting Abstracts

10 Jun 2024

Publications

First-in-man study of the PSMA Minibody IR800-IAB2M for molecularly targeted intraoperative fluorescence guidance during radical prostatectomy

10 Jun 2024

Abstract Presentations

ASCO 2024 Abstract Presentation

03 Jun 2024

Article

Unveiling the Power of CD8 ImmunoPET: A Journey into the Basics and Significance

29 Apr 2024

Article

Shedding Light on Drug Mechanisms: Unveiling Insights with CD8 ImmunoPET

19 Apr 2024

Abstract Presentations

AACR 2024 Poster Presentations

09 Apr 2024

Abstract Presentations

SITC 2023 | Preliminary results of a prospective pilot study using CD8 ImmunoPET imaging to evaluate the immune response to radiation therapy (ELIXR), presented by City of Hope.

10 Nov 2023

Abstract Presentations

SITC 2023 | Takeda | Prediction of Response to Immunotherapy using Machine Learning and Tumor Kinetic Modeling incorporating CD8 ImmunoPET Imaging Analysis

10 Nov 2023

Abstract Presentations

ASCO Poster | CD8 cell PET imaging with 89-Zr-crefmirlimab berdoxam (crefmirlimab) in patients with metastatic renal cell carcinoma (mRCC) receiving checkpoint inhibitors (CPIs): Association with response and tissue CD8 expression

05 Jun 2023

Publications

Radboud UMC Case Report: Imaging immune checkpoint inhibitor-induced yin-yang effects in the brain

01 Jun 2023

Publications

Tubebingen / Theranostics | In vivo imaging of CD8+ T cells in metastatic cancer patients: first clinical experience with simultaneous [89Zr]Zr-Df-IAB22M2C PET/MRI

17 Apr 2023

Abstract Presentations

AACR 2023 AZ Poster | A first assessment of CD8-PET/CT with 89-Zr-Crefmirlimab as predictive biomarker for response to standard of care immunotherapy

15 Apr 2023

Publications

UC Davis pre-peer review publication | First in human immunoPET imaging of COVID-19 convalescent patients using dynamic total-body PET and a CD8 Targeted minibody

31 Mar 2023

Publications

Immune Image Paper | Preclinical PET/CT imaging of colon-infiltrating CD4 + T cells with 89Zr-df-IAB46 in a dextran sodium sulfate-induced mouse model of acute and chronic ulcerative colitis

31 Mar 2023

Abstract Presentations

Radbound UMC Poster | CD8 ImmunoPET evaluated to assess the in vivo biodistribution of CD8+ T cells in hospitalized COVID-19 patients

31 Mar 2023

Publications

'A Transformational Year' 2022 Business Update

19 Dec 2022

Publications

Immuno-PET Monitoring of CD8+ T Cell Infiltration Post ICOS Agonist Antibody Treatment Alone and in Combination with PD 1 Blocking Antibody Using a 89Zr Anti CD8+ Mouse Minibody in EMT6 Syngeneic Tumor Mouse

24 Oct 2022

Publications

Case Studies

PET imaging of CD8+ T-cells using 89Zr-Crefmirlimab berdoxam in healthy Non-Human Primates

03 Oct 2022

Videos

Hear from the experts - What is the greatest value of CD8 imaging in IO clinical trials?

13 Sep 2022

BD Newsletter

August Newsletter - featuring 'What Pharma Wants'

31 Aug 2022

Publications

'What Pharma Wants' survey summary

31 Aug 2022

Publications

Positron Emission Tomography (PET) Imaging in Drug Development, from bench to bedside application, with decision making capabilities

31 Aug 2022

BD Newsletter

July Edition 2022

28 Jul 2022

ImaginAb Data

Case Studies

Abstract Presentations

Preclinical: The PET-Tracer 89Zr-Df-IAB22M2C Enables Monitoring of Intratumoral CD8 T-cell Infiltrates in Tumor-Bearing Humanized Mice after T-cell Bispecific Antibody Treatment - AACR Journal

12 May 2022

ImaginAb Data

Case Studies

Abstract Presentations

Preclinical: Abstract LB-188: Sensitivity of 89Zr-labeled anti-CD8 minibody for PET imaging of infiltrating CD8+ T cells AACR

12 May 2022

ImaginAb Data

Case Studies

Abstract Presentations

Preclinical: Pet imaging of cytotoxic human T cells using an 89Zr-labeled anti-CD8 minibody

12 May 2022

ImaginAb Data

Case Studies

Abstract Presentations

Clinical: O49 - Imaging of tumor infiltrating T cells with an anti-CD8 minibody 89Zr-IAB22M2C in advanced solid tumors: a phase I first-in-human study - SITC 2018

12 May 2022

ImaginAb Data

Case Studies

Abstract Presentations

Clinical: CD8 Positron Emission Tomography (PET/CT) Imaging with89Zr-Df-IAB22M2C in Patients with Inclusion Body Myositis

12 May 2022

ImaginAb Data

Clinical: Abcuro and ImaginAb Share Initial Results of Study Using Novel Technology for Imaging T Cell Infiltration of Skeletal Muscle in Patients with Inclusion Body Myositis

12 May 2022

ImaginAb Data

Publications

Case Studies

Clinical: First-in-Humans Imaging with 89Zr-Df-IAB22M2C Anti-CD8 Minibody in Patients with Solid Malignancies: Preliminary Pharmacokinetics, Biodistribution, and Lesion Targeting

12 May 2022

ImaginAb Data

Publications

Case Studies

Clinical: CD8-Targeted PET Imaging of Tumor-Infiltrating T Cells in Patients with Cancer: A Phase I First-in-Humans Study of 89Zr-Df-IAB22M2C, a Radiolabeled Anti-CD8 Minibody

12 May 2022

ImaginAb Data

Abstract Presentations

Clinical: A Phase IIB, Open-Label Study of Zirconium Zr-89 Crefmirlimab Berdoxam PET

12 May 2022

ImaginAb Data

Case Studies

Abstract Presentations

Clinical: Imaging of CD8+ cytotoxic T-cells by Zr-89-Df-IAB22M2C PET/MRI: First clinical experience in patients with metastatic cancer

12 May 2022

ImaginAb Data

Abstract Presentations

Preclinical: Evaluating immune checkpoint blockade treatment efficacy via [89Zr]-CD4 and [89Zr]-CD8 PET imaging in breast cancer mouse models

12 May 2022

ImaginAb Data

Videos

Clinical: ImaginAb Round Table 2 Webinar Full Video - 31st March 2022 - Exploring the value of CD8 ImmunoPET may offer in drug pipeline development in immunotherapy clinical trials

10 May 2022

ImaginAb Data

Videos

Clinical: Round Table Q&A - 2nd December - Imaging may improve decision making in early IO clinical trials

14 Jan 2022

ImaginAb Data

Videos

Clinical: ImaginAb Round Table Webinar Full Video - 2nd December 2021 - Imaging may improve decision making in early IO clinical trials

13 Jan 2022

ImaginAb Data

Publications

Preclinical: Imaging Tumor-Infiltrating Lymphocytes in Brain Tumors [64Cu with ]Cu-NOTA-anti-CD8 PET

21 Jun 2021

Videos

Video: Imaging in Immunotherapy: Using PET Scans to Guide Cancer Treatment with Kim A. Margolin, M.D.

21 Jun 2021

Publications

Preclinical Evaluation of 89Zr-Df-IAB22M2C PET as an Imaging Biomarker for the Development of the GUCY2C-CD3 Bispecific PF-07062119 as a T Cell Engaging Therapy

21 Jun 2021

Videos

Video: An Introduction to ImaginAb Technology

08 Jun 2021

Publications

ImaginAb Aims to Help Our Immune Systems Better Detect Late-Stage Cancer

08 Jun 2021

Publications

Abstract Presentations

Arming antibodies: prospects and challenges for immunoconjugates

08 Jun 2021

Publications

Abstract Presentations

Antibodies for molecular imaging of cancer

08 Jun 2021

ImaginAb Data

Publications

Abstract Presentations

Preclinical: Site-specific, thiol-mediated conjugation of fluorescent probes to cysteine-modified diabodies targeting CD20 or HER2

08 Jun 2021

ImaginAb Data

Publications

Abstract Presentations

Preclinical: Positive progress in immunoPET - not just a coincidence

08 Jun 2021

ImaginAb Data

Publications

Abstract Presentations

Preclinical: Evaluation of Engineered Antibody Fragments Directed to Prostate Stem Cell Antigen (PSCA) in Moderate and Low PSCA Expressing Pancreatic Tumor Xenografts Using PET Imaging

08 Jun 2021

ImaginAb Data

Case Studies

Abstract Presentations

Preclinical: Nonradioactive Analytical Methods for Quantifying the Modification Ratio of Antibody Fragment Chelator Conjugates with Deferroxamine and NODAGA

08 Jun 2021

ImaginAb Data

Publications

Case Studies

Abstract Presentations

Preclinical: ImmunoPET Imaging of Prostate Stem Cell Antigen (PSCA) in Pancreatic Xenografts: Comparison of Intact IgG with Engineered Antibody Fragments

08 Jun 2021

ImaginAb Data

Case Studies

Abstract Presentations

Preclinical: Evaluation of two engineered antibody fragments, derived from the human anti-CD20 Ofatumumab, as tracers for immunoPET

08 Jun 2021

ImaginAb Data

Publications

Case Studies

Abstract Presentations

Preclinical: Quantitative immunoPET of prostate cancer xenografts with 89Zr- and 124I-labeled anti-PSCA A11 minibody

08 Jun 2021

ImaginAb Data

Case Studies

Abstract Presentations

Preclinical: Optimization of Desferrioxamine Conjugation to a Cytotoxic ADC for In Vivo PET Imaging Studies

08 Jun 2021

ImaginAb Data

Case Studies

Abstract Presentations

Preclinical: 89Zr-Df-IAB2M Minibody Imaging In Patients With Prostate Cancer: Biodistribution, Kinetics, Lesion Uptake And Organ Dosimetry

08 Jun 2021

ImaginAb Data

Case Studies

Abstract Presentations

Preclinical: Head-to-Head Comparison of 89Zr-Df-IAB2M PET/CT to 111 In-Capromab Pendetide SPECT/CT Scans in the Detection of Occult Prostate Cancer in Patients Undergoing Radical Prostatectomy (RP) with Negative Conventional Imaging (CI) Studies

08 Jun 2021

ImaginAb Data

Case Studies

Abstract Presentations

Clinical: Use of Virtual Dose Reconstruction for Optimization of 89Zr-Df-IAB2M Administered Activity in the Detection of Metastatic Prostate Cancer by PET/CT

08 Jun 2021

ImaginAb Data

Case Studies

Abstract Presentations

Clinical: Comparison Of 89Zr-Df-IAB2M PET/CT To 111 In Capromab Pendetide SPECT/CT In The Detection Of Occult Prostate Cancer In Patients Undergoing Radical Prostatectomy (RP) In a Single Center Phase II Study

08 Jun 2021

ImaginAb Data

Clinical: New PET imaging agent detects mestatic prostate cancer Dec 2016

08 Jun 2021

ImaginAb Data

Case Studies

Abstract Presentations

Preclinical: Development of an ImmunoPET Tracer for Imaging Human CD8+ T Cells

08 Jun 2021

ImaginAb Data

Case Studies

Abstract Presentations

Preclinical: Anti-CD8 immunoPET detection of CD8+ tumor infiltrating lymphocytes

08 Jun 2021

ImaginAb Data

Publications

Case Studies

Preclinical: Engineered antibody fragments for immuno-PET imaging of endogenous CD8+ T cells in vivo

08 Jun 2021

ImaginAb Data

Case Studies

Abstract Presentations

Preclinical: PET Imaging of Cytotoxic Human T Cells Using an 89Zr-Labeled Anti-CD8 Minibody

08 Jun 2021

ImaginAb Data

Videos

Video: How CD8 Imaging is Useful to Pharma Regarding Drug Research & Clinical Decision Making

08 Jun 2021

Publications

How can AI change the industry? Faster diagnoses and improved treatment options

08 Jun 2021

Publications

Can in vivo imaging deliver the full potential of immunotherapy?

08 Jun 2021

Publications

A new approach to molecular imaging in cancer patients

08 Jun 2021

ImaginAb Data

Publications

First-in-human imaging with 89Zr-Df-IAB22M2C anti-CD8 minibody in patients with solid malignancies

08 Jun 2021

Publications

PET imaging sheds light on immunotherapy response

02 Jun 2021

Knowledge Hub

Speak with one of our experts to learn how you can license CD8 ImmunoPET™ in your clinical trials.

Speak with one of our experts to learn how you can license CD8 ImmunoPET™ in your clinical trials.